Recent journal covers from the Pathak Lab

Dr. Pathak's Google Scholar Profile

PUBLICATIONS

 

  • Pak RW, Hadjiabadi D, Senarathna J, Agarwal S, Thakor NV, Pillai JJ and Pathak AP, “Implications of neurovascular uncoupling in functional magnetic resonance imaging (fMRI) of brain tumors”, J Cereb Blood Flow Metab. 2017 (in press).

  • Penet MF, Kakkad S, Pathak AP, Krishnamachary B, Mironchik Y, Raman V, Solaiyappan M, Bhujwalla ZM, “Structure and Function of a Prostate Cancer Dissemination-Permissive Extracellular Matrix”, Clin Cancer Res. May 1;23(9):2245-2254, 2017.

  • Krishnamachary B, Stasinopoulos I, Kakkad S, Penet MF, Jacob D, Wildes F, Mironchik Y, Pathak AP, Solaiyappan M, Bhujwalla ZM, “Breast cancer cell cyclooxygenase-2 expression alters extracellular matrix structure and function and numbers of cancer associated fibroblasts”, Oncotarget. Mar 14;8(11):17981-17994, 2017.

  • O'Connor JP, Aboagye EO, Adams JE, Aerts HJ, Barrington SF, Beer AJ, Boellaard R, Bohndiek SE, Brady M, Brown G, Buckley DL, Chenevert TL, Clarke LP, Collette S, Cook GJ, deSouza NM, Dickson JC, Dive C, Evelhoch JL, Faivre-Finn C, Gallagher FA, Gilbert FJ, Gillies RJ, Goh V, Griffiths JR, Groves AM, Halligan S, Harris AL, Hawkes DJ, Hoekstra OS, Huang EP, Hutton BF, Jackson EF, Jayson GC, Jones A, Koh DM, Lacombe D, Lambin P, Lassau N, Leach MO, Lee TY, Leen EL, Lewis JS, Liu Y, Lythgoe MF, Manoharan P, Maxwell RJ, Miles KA, Morgan B, Morris S, Ng T, Padhani AR, Parker GJ, Partridge M, Pathak AP, Peet AC, Punwani S, Reynolds AR, Robinson SP, Shankar LK, Sharma RA, Soloviev D, Stroobants S, Sullivan DC, Taylor SA, Tofts PS, Tozer GM, van Herk M, Walker-Samuel S, Wason J, Williams KJ, Workman P, Yankeelov TE, Brindle KM, McShane LM, Jackson A, Waterton JC, “Imaging biomarker roadmap for cancer studies”, Nat Rev Clin Oncol. 2017 Mar;14(3):169-186, 2017.
  • Fortenberry YM, Brandal SM, Carpentier G, Hemani M, Pathak AP, “Intracellular Expression of PAI-1 Specific Aptamers Alters Breast Cancer Cell Migration, Invasion and Angiogenesis”, PLoS One. Oct 18;11(10):e0164288, 2016.
  • Yu H, Senrathna J, Tyler BM, Thakor NV, Pathak AP, “Miniaturized optical neuroimaging in unrestrained animals”, Neuroimage. Jun;113:397-406, 2015.
  • Cebulla J, Huuse EM, Pettersen K, van der Veen A, Kim E, Andersen S, Prestvik WS, Bofin AM, Pathak AP, Bjørkøy G, Bathen TF, Moestue SA, “MRI reveals the in vivo cellular and vascular response to BEZ235 in ovarian cancer xenografts with different PI3-kinase pathway activity”, Br J Cancer. Feb 3;112(3):504-13 2015.
  • Kim E, Lee E, Plummer C, Gil S, Popel AS, Pathak AP, “Vasculature-specific MRI reveals differential anti-angiogenic effects of a biomimetic peptide in an orthotopic breast cancer model”, Angiogenesis. Apr;18(2):125-36, 2015.
  • Schunke KJ, Toung TK, Zhang J, Pathak AP, Xu J, Zhang J, Koehler RC, Faraday N, “A Novel Atherothrombotic Model of Ischemic Stroke Induced by Injection of Collagen into the Cerebral Vasculature”, J Neurosci Methods. Jan 15;239:65-74, 2015.
  • Cebulla J, Kim E, Rhie K, Zhang J, Pathak AP, “Multiscale and multi-modality visualization of angiogenesis in a human breast cancer model”, Angiogenesis. Jul; 17(3):695-709, 2014 – JOURNAL COVER.
  • Stamatelos S, Kim E, Pathak AP and Popel AS.  “A Bioimage Informatics Based Reconstruction of Breast Tumor Microvasculature with Computational Blood Flow Predictions”, Microvasc Res. Jan; 91: 8-21, 2014 – JOURNAL COVER.
  • Kakkad SM, Penet M-F, Akhbardeh A, Pathak AP, Solaiyappan M, Raman V, Leibfritz D, Glunde K and Bhujwalla ZM, “Hypoxic Tumor Environments Exhibit Disrupted Collagen I Fibers and Low Macromolecular Transport”, PLoSOne, Dec 12;8(12): e818692013, 2013.
  • Pathak AP, McNutt S, Shah T, Wildes F, Raman V, Bhujwalla ZM. “MRI Phenotyping" Reveals Changes in Extracellular Matrix Transport and Vascularization that Mediate VEGF-driven Increase in Breast Cancer Metastasis”, PLoS One, May 1; 8(5):e63146, 2013.
  • Grossman R, Tyler B, Rudek MA, Kim E, Zadnik P, Khan U, Blakeley JO, Pathak AP, Brem H. “Microdialysis Measurement of Intratumoral Temozolomide Concentration after Cediranib, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, in a U87 Glioma Model”, Cancer Chemother Pharmacol, May 7, 2013 [Epub ahead of print].
  • Kim E, Cebulla J, Ward BD, Rhie K, Zhang J, and Pathak AP. “Assessing Breast Cancer Angiogenesis In vivo: Which Susceptibility Contrast MRI Biomarkers Are Relevant?”, Mag Reson Med, 2013. [Epub ahead of print]
  • Kim E, Stamatelos S, Cebulla J, Bhujwalla ZM, Popel AS and Pathak AP. “Multiscale Imaging and Computational Modeling of Blood Flow in the Tumor Vasculature”, Ann of Biomed Eng 2012 May 8. [Epub ahead of print] – JOURNAL COVER.
  • Rege A, Thakor NV, Pathak AP. “Optical Imaging of Microvascular Morphology and Perfusion”, Current Angiogenesis, 1(3):243-60, 2012 – JOURNAL COVER.
  • Rege A, Thakor NV, Rhie K, Pathak AP. “In vivo laser speckle imaging reveals microvascular remodeling and hemodynamic changes during wound healing angiogenesis”, Angiogenesis, 15(1):87-98. Epub Dec 24, 2012 – JOURNAL COVER.
  • Pathak AP, Kim E, Zhang J, Jones MV. “Three-dimensional imaging of the mouse neurovasculature with magnetic resonance microscopy”, PLoS One. 6(7): e22643. Epub Jul 27, 2011.
  • Rege A, Murari K, Seifert A, Pathak AP, Thakor NV. “Multiexposure laser speckle contrast imaging of the angiogenic microenvironment”, J Biomed Opt. 16(5):056006, 2011.
  • Kim E, Zhang J, Hong K, Benoit NE, Pathak AP. “Vascular phenotyping of brain tumors using magnetic resonance microscopy (μMRI)”, J Cereb Blood Flow Metab. 31(8): 1817-8, 2011 – JOURNAL COVER.
  • Penet MF, Mikhaylova M, Li C, Krishnamachary B, Glunde K, Pathak AP, Bhujwalla ZM, “Applications of molecular MRI and optical imaging in cancer”, Future Med Chem, 2(6):975-988, 2010.
  • Pathak AP, Penet M, and Bhujwalla ZM, “MR Molecular Imaging of Tumor Vasculature and Vascular Targets”, Advances in Genetics, 69:1-30, 2010.
  • Soong TR, Pathak AP, Asano H, Fox-Talbot K and Baldwin WM 3rd, “Lymphatic Injury And Regeneration In Cardiac Allografts”, Transplantation, 89(5):500-8, 2010.
  • Pathak AP. “Model system takes us a step closer to efficacious imaging biomarkers of angiogenesis in head and neck cancer”, Cancer Biol Ther; 8(23):2284-5, 2010.
  • Penet M, Pathak AP, Raman V, Ballesteros P, Artemov D and Bhujwalla ZM, “Noninvasive Multi-parametric Imaging of Metastasis-Permissive Microenvironments in a Human Prostate Cancer Xenograft”, Cancer Research; 69(22):8822-9. 2009.
  • Penet M, Mikhaylova M, Li C, Krishnamachary B, Glunde K, Pathak AP,  Bhujwalla ZM, “Applications of molecular MRI and optical imaging in cancer.”, Medicinal Chemistry Reviews, Future Med Chem. Jun;2(6):975-988.2010.
  • Pathak AP, “MR Susceptibility-based Perfusion Imaging of Tumors using Iron Oxide Nanoparticles”, Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology; 1(1):84-97, 2009.
  • Pathak AP, Hochfeld WE, Goodman SL, Pepper MS, “Circulating and imaging markers for angiogenesis”, Angiogenesis, 11(4):321-335, 2008.
  • Glunde K, Jacobs MA, Pathak AP, Artemov D, Bhujwalla ZM, “Molecular and functional imaging of breast cancer”, NMR Biomed. Sep 15. [Epub ahead of print] 2008.
  • Winnard PT, Pathak AP, Dhara S, Cho SY, Raman V and Pomper MG, “Molecular Imaging of Metastatic Potential”, J Nucl Med, 49: 96S-112S, 2008.
  • Penet M-F, Glunde K, Jacobs MA, Pathak AP and Bhujwalla ZM, “MR Molecular and Functional Imaging of the Tumor Microenvironment”, J Nucl Med, May; 49(5):687-90, 2008.
  • Pathak AP, Ward BD, and Schmainda KM, “A Novel Technique for Modeling Susceptibility-Based Contrast Mechanisms for Arbitrary Microvascular Geometries: The Finite Perturber Method”, NeuroImage; 40(3):1130-1143, 2008.
  • Glunde K, Pathak AP, Bhujwalla ZM, “Molecular-functional imaging of cancer: to image and imagine”, Trends Mol Med. 13(7):287-97, 2007.
  • Raman V, Pathak AP, Glunde K, Artemov D and Bhujwalla ZM, “Magnetic Resonance Imaging and Spectroscopy of Transgenic Models of Cancer”, NMR Biomed. May; 20(3):186-99, 2007.
  • Raman V, Artemov D, Pathak AP, Winnard PT, Yudina A, Bogdanov A, and Bhujwalla ZM, "Hypoxic regions are characterized by low vascular volume and high permeability: A combined MR and optical imaging study of a human prostate cancer model", Cancer Research, 66(20):9929-36, 2006.
  • Pathak AP, Artemov D, Neeman M, and Bhujwalla ZM. “Lymph node metastasis in breast cancer xenografts is associated with increased regions of extravascular drain, lymphatic vessel area and invasive phenotype”, Cancer Research, 66(10):5151-58, 2006.
  • Pathak AP. “Magnetic resonance imaging of tumor physiology”, Methods Mol Med, 124:279-97, 2006.
  • Gimi B, Pathak AP, Ackerstaff E, Glunde K, Artemov D and Bhujwalla ZM.  “Molecular Imaging Of Cancer: Applications of MR Methods”, Proceedings of the IEEE, v93:784-799, 2005.
  • Mironchik Y, Winnard P, Vesuna F, Kato Y, Wildes F, Pathak AP, Kominsky S, Artemov D, Bhujwalla ZM, vanDiest P, Burger H, Glackin C and Raman V.  “Twist overexpression induces in vivo angiogenesis and correlates with chromosomal instability in breast cancer”, Cancer Research, 65(23):10801-9, 2005.
  • Pathak AP, Artemov D, Ward DB, Jackson DG, Neeman M, and Bhujwalla ZM. “Characterizing extravascular fluid transport of macromolecules in the tumor interstitium by MRI”, Cancer Research, 65(4):1425-32, 2005.
  • Pathak AP, Gimi B, Glunde K, Ackerstaff E, Artemov D and Bhujwalla ZM.  “Molecular And Functional Imaging Of Cancer: Advances in MRI and MRS”, Methods in Enzymology: Imaging in Biol Research, Part B, v386: 1-58, 2004.
  • Pathak AP, Bhujwalla ZM and Pepper MS.  “Visualizing Function in the Tumor-Associated Lymphatic System”, Lymphatic Research in Biology, 2(4):165-72, 2004.
  • Pathak AP, Dmitri A, and Bhujwalla ZM.  “A Novel System for Continuous In Vivo Monitoring of Contrast Dynamics in a Mouse Tumor Model”, Magnetic Resonance in Medicine, 51(3):612-615, 2004.
  • Schmainda KM, Rand SD, Joseph AM, Lund R, Ward BD, Pathak AP, Ulmer JL, Baddrudoja MA, Krouwer HG.  “Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis”, Am J Neuroradiol. Oct; 25(9):1524-32. 2004
  • Glunde K, Guggino, SE, Solaiyappan M, Pathak AP, Ichikawa Y and Bhujwalla ZM.  “Extracellular Acidification Alters Lysosomal Trafficking In Human Breast Cancer Cells”, Neoplasia, 5(6): 533-545, 2003.
  • Pathak AP, Rand SD, and Schmainda KM. “The Effect of Brain Tumor Angiogenesis on the In Vivo Relationship between the Gradient Echo Relaxation Rate Change (DR2*) and Contrast Agent (MION) Dose”, Journal of Magnetic Resonance Imaging, 18(4): 397-403, 2003.
  • Biswal BB, Pathak AP, Ulmer JL, and Hudetz AG.  “Decoupling of the Hemodynamic and Activation-Induced Delays in fMRI”, Journal of Computer Assisted Tomography, 27(2): 219-225, 2003.
  • Badruddoja MA, Krouwer HG, Rand SD, Rebro KJ, Pathak AP, and Schmainda KM. “Anti-Angiogenic Effects of Dexamethasone in 9L Gliosarcoma Assessed by MRI Cerebral Blood Volume Maps”, Neuro-oncology, 5(4): 235-243, 2003 – JOURNAL COVER.
  • Pathak AP, Schmainda KM, Ward BD, Linderman JR, Rebro KJ, and Greene AS.  “MR-derived Cerebral Blood Volume Maps: Issues Regarding Histological Validation and Assessment of Tumor Angiogenesis”, Magnetic Resonance in Medicine, 46(4): 735-747, 2001.
  • Donahue KM, Krouwer HG, Rand SD, Pathak AP, Marszalkowski CS, Censky SC, Prost RW. “Utility of simultaneously acquired gradient-echo and spin-echo cerebral blood volume and morphology maps in brain tumor patients”, Magnetic Resonance in Medicine, 43(6): 845-853, 2000.
  • Pathak AP, Silver-Thorn MB.  “A Rate Controlled Indent or for In Vivo Analysis of Residual Limb Tissues”, IEEE Transactions on Rehabilitation Engineering, 6(1): 16-30, 1998.